May 26, 2018

Efficient tools for large-scale multiple alignments of genomic DNA

The Lagan Tookit is a set of alignment programs for comparative genomics. The three main components are a pairwise aligner LAGAN, a multiple aligner M-LAGAN, and a glocal aligner Shuffle-LAGAN. All three are based on the CHAOS local alignment tool and combine speed regions up to several megabases can be aligned in minutes with high accuracy. The results of the alignment can be visualized using the VISTA visualization tool.

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